BDBM50245294 6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-N-(4-(trifluoromethyl)phenyl)-1H-indazol-3-amine::CHEMBL516639

SMILES COc1cc2nccc(Oc3ccc4c(Nc5ccc(cc5)C(F)(F)F)nn(C)c4c3)c2cc1OC

InChI Key InChIKey=UXFAPZKWKVGBBM-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50245294   

TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50245294(6-(6,7-dimethoxyquinolin-4-yloxy)-1-methyl-N-(4-(t...)
Affinity DataIC50:  70nMAssay Description:Inhibition of recombinant KDR by HTRF assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed